Ascaso Terrén Carlos, Garcia Esteve Lluïsa, Navarro Puri, Aguado Jaume, Ojuel Julia, Tarragona M Jesús
Departament de Salut Pública, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Universitat de Barcelona, Spain.
Med Clin (Barc). 2003 Mar 15;120(9):326-9.
Our objectives were: To estimate the prevalence of postpartum depression (PD) by two evaluation methods: Structured Clinical Interview for DSM-IV (SCID), and self-report Edinburgh Postnatal Depression Scale (EPDS), and to identify the EPDS cut-off to provide an unbiased estimation of PD prevalence.
We report data from all women (n = 1191) attending to postnatal routine checking visits at six weeks postpartum during one year in the Gynaecology and Obstetrics Department of the Hospital Clínic of Barcelona (Spain). A two-stage method was used. In the first stage, all women selected completed the EPDS. In the second stage, all women with an EPDS score >= 9 (probable PD cases) and a randomized sample of 16% with a score < 9 were evaluated by a psychiatrist using the SCID interview to establish a psychiatric diagnosis of major and minor depression. 402 postpartum women were offered the SCID interview; 68 of them refused to participate.
The prevalence of depression according to the SCID interview was 10.15% (CI 95%, 8.43-11.87). The prevalence of major depression was 3.6% (CI 95%, 2.55-4.67) and it was 6.5% (CI 95%, 5.14-7.95) for minor depression. An EPDS cut-off of 11/12 provided an unbiased estimation of the postpartum depression prevalence rate.
Our results justify the need to use different EPDS cut-offs. A cut-off of 10/11 is effective for identifying the population at risk and a cut-off of 11/12 is useful to estimate the prevalence in epidemiological studies.
我们的目标是:通过两种评估方法估计产后抑郁症(PD)的患病率:《精神疾病诊断与统计手册》第四版结构化临床访谈(SCID)和自我报告的爱丁堡产后抑郁量表(EPDS),并确定EPDS的临界值以无偏估计PD患病率。
我们报告了西班牙巴塞罗那临床医院妇产科一年内产后六周进行产后常规检查的所有女性(n = 1191)的数据。采用两阶段方法。在第一阶段,所有入选女性完成EPDS。在第二阶段,所有EPDS评分≥9(可能的PD病例)的女性以及16%评分<9的随机样本由精神科医生使用SCID访谈进行评估,以确立重度和轻度抑郁症的精神科诊断。402名产后女性接受了SCID访谈;其中68人拒绝参与。
根据SCID访谈,抑郁症患病率为10.15%(95%CI,8.43 - 11.87)。重度抑郁症患病率为3.6%(95%CI,2.55 - 4.67),轻度抑郁症患病率为6.5%(95%CI,5.14 - 7.95)。EPDS临界值为11/12可无偏估计产后抑郁症患病率。
我们的结果证明需要使用不同的EPDS临界值。临界值为10/11对于识别高危人群有效,临界值为11/12对于在流行病学研究中估计患病率有用。