Lévy G, Bordes F, Mariottini P, François G
Nouv Presse Med. 1976 Jan 31;5(5):251-4.
The number, volume and adhesive and aggregation activities of platelets were studied in 31 patients with artificial valves. The differences observed in comparison with a control population are due to stimulation of thrombocytopoiesis secondary to the destruction or concumption of the platelets, it being impossible to be sure as to the dominant mechanism. Under these circumstances it would seem important in each patient to verify the therapeutic effectiveness of platelet inhibitors or of traditionnal anticoagulants by direct or indirect study of platelet life duration.
对31例人工瓣膜患者的血小板数量、体积以及黏附与聚集活性进行了研究。与对照组相比所观察到的差异是由于血小板破坏或消耗继发的血小板生成刺激所致，目前尚无法确定主要机制。在这种情况下，通过直接或间接研究血小板寿命来验证血小板抑制剂或传统抗凝剂对每位患者的治疗效果似乎很重要。
