López-Caballero C, Saornil-Alvarez M A, Blanco-Mateos G, Frutos-Baraja J M, López-Lara F, González-Sansegundo C
Hospital Clínico Universitario de Valladolid, Valladolid, España.
Arch Soc Esp Oftalmol. 2003 Feb;78(2):99-102.
We present four cases of ocular melanosis. Choroidal melanoma was detected in all of them. Three eyes had decreased visual acuity and were enucleated because of their large, active tumours. In the fourth case the melanoma was detected in a routine examination and we were able to apply a preserving treatment with I125 brachytherapy.
Melanosis oculi is often underestimated as a risk factor for uveal melanoma and glaucoma. Ophthalmic surveillance, every 6 or 12 months is important, in patients with ocular melanocytosis for early detection of high risk diseases.
我们报告了4例眼黑变病病例。所有病例均检测出脉络膜黑色素瘤。3只眼视力下降，因肿瘤大且活跃而行眼球摘除术。在第4例中，黑色素瘤在常规检查中被发现，我们对其采用了碘125近距离放疗的保留治疗方法。
眼黑变病作为葡萄膜黑色素瘤和青光眼的危险因素常被低估。对于患有眼黑变病的患者，每6或12个月进行一次眼科监测对于早期发现高危疾病很重要。
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