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抗艾滋病病毒药物的最新进展——即将面市的三种药物

Anti-HIV drug updates--three drugs on the near horizon.

出版信息

Proj Inf Perspect. 2003 Jan(35):4-7.

Abstract

The most significant new information about anti-HIV drugs offered in Barcelona concerned those drugs that are either already available or which will soon be available. This includes new information about T-20 (now called enfuvirtide or Fuzeon) and atazanavir--two drugs which will likely be approved within the next six months. Another new drug likely to be approved soon is FTC (Coviracil), a close relative of 3TC (lamivudine, Epivir), though its importance is less certain than that of enfuvirtide and atazanavir. Important new information was also released about tenofovir (Viread), a drug approved by the FDA late in 2001. Equally important were new observations about some older drugs, particularly the combination of ddI and d4T. Many comparative studies of different drug combinations were also reported, offering new information about the relative value of a number of treatment strategies.

摘要

在巴塞罗那提供的有关抗艾滋病毒药物的最重要新信息涉及那些已上市或即将上市的药物。这包括有关T - 20(现称恩夫韦肽或福泽昂)和阿扎那韦的新信息——这两种药物可能会在未来六个月内获批。另一种可能很快获批的新药是FTC(科韦拉西尔),它是3TC(拉米夫定,贺普丁)的近亲,不过其重要性不如恩夫韦肽和阿扎那韦那么确定。有关替诺福韦(韦瑞德)也发布了重要新信息,该药物于2001年末获美国食品药品监督管理局批准。同样重要的是对一些较老药物的新观察结果,特别是去羟肌苷和司他夫定的联合使用。还报告了许多不同药物组合的比较研究,提供了有关多种治疗策略相对价值的新信息。

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