Hjelmstedt Anna, Widström Ann-Marie, Wramsby Håkan, Matthiesen Ann-Sofi, Collins Aila
Department of Woman and Child Health, Karolinska Institutet, Stockholm, Sweden.
Acta Obstet Gynecol Scand. 2003 Feb;82(2):152-61. doi: 10.1034/j.1600-0412.2003.00040.x.
Little is known as to whether negative experiences associated with infertility and IVF treatment persist after successful treatment. The aim of the study was to compare couples who have conceived after IVF and couples who have conceived naturally regarding personality factors and emotional responses to pregnancy.
Fifty-seven women pregnant after IVF and 55 male partners and 43 women who had conceived naturally and 39 male partners were recruited from university IVF clinics and antenatal clinics in Stockholm. The subjects were interviewed about their socio-demographic background. They completed scales of personality traits, anxiety, emotional responses to pregnancy, marital adjustment and reactions to recalled infertility while in pregnancy week 13 (range 11-17).
The results showed that the IVF women had more muscular tension and were more anxious about loosing the pregnancy than the control women. The IVF women with high infertility distress were more anxious about loosing the pregnancy and less ambivalent than the women with lower distress. The IVF men had more somatic anxiety, indirect aggression, guilt, and were more detached and more anxious about loosing the pregnancy and less ambivalent than the control men. The IVF men with high infertility distress were more anxious about the baby not being normal than the men with lower infertility distress.
The women and men who had conceived after IVF differed on a number of personality dimensions and emotional responses to the pregnancy from that of the women and the men who had conceived naturally. The results suggest that IVF couples may need additional emotional support in early pregnancy.
关于与不孕症及体外受精（IVF）治疗相关的负面经历在治疗成功后是否依然存在，目前所知甚少。本研究的目的是比较通过IVF受孕的夫妇和自然受孕的夫妇在人格因素及对怀孕的情绪反应方面的差异。
从斯德哥尔摩的大学IVF诊所和产前诊所招募了57名IVF后怀孕的女性及其55名男性伴侣，以及43名自然受孕的女性及其39名男性伴侣。对受试者进行了社会人口学背景访谈。他们在怀孕第13周（范围为11 - 17周）时完成了人格特质、焦虑、对怀孕的情绪反应、婚姻调适以及对回忆起的不孕症的反应等量表。
结果显示，与对照组女性相比，IVF女性有更多的肌肉紧张，并且对失去妊娠更为焦虑。不孕症困扰程度高的IVF女性比困扰程度低的女性对失去妊娠更焦虑，且矛盾心理更少。与对照组男性相比，IVF男性有更多的躯体焦虑、间接攻击性、内疚感，更加冷漠，对失去妊娠更焦虑，矛盾心理更少。不孕症困扰程度高的IVF男性比困扰程度低的男性更担心胎儿不正常。
通过IVF受孕的女性和男性在一些人格维度及对怀孕的情绪反应方面与自然受孕的女性和男性存在差异。结果表明，IVF夫妇在孕早期可能需要额外的情感支持。
