Sanders Toni R, Roberts Christine L, Gilbert Gwendolyn L
Department of Public Health, University of Sydney, Australia.
Infect Dis Obstet Gynecol. 2002;10(4):223-9. doi: 10.1155/S1064744902000261.
The aim of this study was to determine the prevalence of clinical risk factors (CRF) for neonatal sepsis in laboring women and to evaluate clinician compliance with a CRF-based protocol for intrapartum antibiotic prophylaxis (IAP).
A retrospective chart audit was undertaken at a district hospital (A) and a tertiary obstetric hospital (B) in Sydney, Australia between 1996 and 1998, to determine compliance with IAP in women with defined CRF.
Eighty-five (12%) women at Hospital A and 117 (19%) at Hospital B had one or more CRF. Overall compliance rates with the IAP protocols were 65 and 50% at Hospitals A and B respectively, but varied according to maternal, obstetric and sepsis-related risk factors. We postulate that differences between the hospitals were related to protocol implementation.
Compliance with a CRF-based protocol was lower than previously reported. Improvements in protocol development, implementation and maintenance are required to enhance compliance with IAP based on CRF.
本研究旨在确定分娩期妇女新生儿败血症临床风险因素（CRF）的患病率，并评估临床医生对基于CRF的产时抗生素预防（IAP）方案的依从性。
1996年至1998年期间，在澳大利亚悉尼的一家地区医院（A）和一家三级产科医院（B）进行了一项回顾性病历审核，以确定患有特定CRF的妇女对IAP的依从性。
A医院有85名（12%）妇女，B医院有117名（19%）妇女有一个或多个CRF。A医院和B医院对IAP方案的总体依从率分别为65%和50%，但因产妇、产科和败血症相关风险因素而异。我们推测医院之间的差异与方案实施有关。
对基于CRF的方案的依从性低于先前报道。需要在方案制定、实施和维护方面加以改进，以提高基于CRF的IAP的依从性。
