Geelhoed Diederike W, Visser Lucia E, Asare Kofi, Schagen van Leeuwen Jules H, van Roosmalen Jos
Holy Family Hospital, Berekum, Region, Brong Ahafo, Ghana.
Eur J Obstet Gynecol Reprod Biol. 2003 Apr 25;107(2):135-9. doi: 10.1016/s0301-2115(02)00224-5.
To measure the impact of the Safe Motherhood Initiative (SMI) on hospital-based maternal mortality since its start in 1987.
Retrospective analysis of all 229 maternal deaths in a district hospital in rural Ghana, between 1 January 1987 and 1 January 2000. Main outcome measures were maternal mortality ratio and relative contribution of causes of maternal deaths to overall maternal mortality. Chi-square test was used to assess differences in proportions, and relative risks with confidence intervals were calculated.
The overall maternal mortality ratio of 1077/100,000 live births did not change significantly during the study period. However, the relative contributions of sepsis, hemorrhage, obstructed labor, anemia/sickle cell disease and (pre-) eclampsia diminished, while abortion complications increased significantly.
The Safe Motherhood Initiative in the study area has contributed to the reduction of maternal mortality due to causes against which interventions were directed. Abortion complications as cause of maternal mortality need to be included in interventions and research.
评估自1987年启动安全孕产倡议(SMI)以来,其对基于医院的孕产妇死亡率的影响。
对1987年1月1日至2000年1月1日期间加纳农村一家区级医院的229例孕产妇死亡病例进行回顾性分析。主要结局指标为孕产妇死亡率以及孕产妇死亡原因对总体孕产妇死亡率的相对贡献。采用卡方检验评估比例差异,并计算相对风险及置信区间。
在研究期间,总体孕产妇死亡率为1077/10万活产,无显著变化。然而,败血症、出血、产程梗阻、贫血/镰状细胞病和(先兆)子痫的相对贡献有所减少,而流产并发症显著增加。
研究区域的安全孕产倡议有助于降低针对特定干预措施的孕产妇死亡原因导致的死亡率。作为孕产妇死亡原因的流产并发症需要纳入干预措施和研究中。