Gormley Karen L, Teather Kevin L
Department of Biology, University of Prince Edward Island, Charlottetown, Prince Edward Island, Canada C1A 4P3.
Ecotoxicol Environ Saf. 2003 Mar;54(3):330-8. doi: 10.1016/s0147-6513(02)00005-2.
Japanese medaka (Oryzias latipes) were exposed to concentrations of 0.01, 0.10, and 1.0 microg/L of the pesticide endosulfan for 24h beginning either 4-6h postfertilization or 4-6h posthatch to determine effects on hatching time, growth, mobility, foraging ability, and reproduction. Eggs exposed to endosulfan took longer to hatch, and the resulting fry were smaller at 1 week of age and had decreased mobility at 2 weeks of age. Upon reaching sexual maturity, these individuals also produced fewer eggs, and these eggs took significantly longer to hatch. Medaka exposed to endosulfan shortly after hatching did not differ in early mobility or foraging ability. Interestingly, upon reaching sexual maturity, these individuals produced more eggs than did unexposed females. The observed effects were not dose-dependent, with medaka exposed to intermediate concentrations of endosulfan (0.10 microg/L) exhibiting the greatest response. These results suggest that short-term exposure to environmentally relevant concentrations of a common pesticide may have long-term effects on growth, behavior, and reproduction in fish.
将日本青鳉（Oryzias latipes）在受精后4 - 6小时或孵化后4 - 6小时开始，暴露于浓度分别为0.01、0.10和1.0微克/升的农药硫丹中24小时，以确定其对孵化时间、生长、活动能力、觅食能力和繁殖的影响。暴露于硫丹的鱼卵孵化时间延长，孵出的鱼苗在1周龄时体型较小，在2周龄时活动能力下降。达到性成熟后，这些个体产卵数量也减少，且这些鱼卵孵化所需的时间显著延长。孵化后不久就暴露于硫丹的青鳉在早期活动能力或觅食能力方面没有差异。有趣的是，达到性成熟后，这些个体比未暴露的雌鱼产卵更多。观察到的影响并非剂量依赖性，暴露于中等浓度硫丹（0.10微克/升）的青鳉表现出最大的反应。这些结果表明，短期暴露于环境相关浓度的常见农药可能会对鱼类的生长、行为和繁殖产生长期影响。
