雌激素和孕激素对大鼠子宫内膜一氧化氮含量的影响。
Effect of estrogen and progestogen on nitric oxide content in rat endometrium.
作者信息
Zha Yuan-ping
机构信息
Department of Obstetrics and Gynecology, Guangzhou General Hospital of Guangzhou Command, Guangzhou 510010, China.
出版信息
Di Yi Jun Yi Da Xue Xue Bao. 2003 Mar;23(3):283.
OBJECTIVE
To observe the effect of estrogen and progestogen on the content of nitric oxide (NO) in the endometrium of SD rats.
METHOD
Fifteen SD rats were divided into control, estrogen and levonorgestrel groups (5 in each group), with corresponding treatment indicated by the designation of the groups. The NO contents in the endometrium were determined by Griess method.
RESULTS
he NO content of estrogen group was significantly higher, while that of levonorgestrel group significantly lower, than that of the control group (P < 0.01 for both comparisons).
CONCLUSIONS
Estrogen and levonorgestrel may regulate NO synthesis in the endometrium.
目的
观察雌激素和孕激素对SD大鼠子宫内膜中一氧化氮（NO）含量的影响。
方法
将15只SD大鼠分为对照组、雌激素组和左炔诺孕酮组（每组5只），根据分组进行相应处理。采用Griess法测定子宫内膜中的NO含量。
结果
雌激素组的NO含量显著高于对照组，而左炔诺孕酮组的NO含量显著低于对照组（两组比较P均<0.01）。
结论
雌激素和左炔诺孕酮可能调节子宫内膜中NO的合成。
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