Halkitis P N, Parsons J T, Wolitski R J, Remien R H
Department of Applied Psychology, New York University, 239 Greene Street, East Building 537G, New York, NY 10003, USA.
AIDS Care. 2003 Feb;15(1):89-102. doi: 10.1080/095401221000039798.
Data regarding HIV antiretroviral treatment regimens, access to treatment and medical care, and adherence to medications were collected as part of the Seropositive Urban Men's Study, a formative study of HIV-positive men who have sex with men. Participants (N = 456) were recruited from AIDS service organizations, mainstream gay venues and public/commercial sex environments. The sample was 94% gay or bisexually-identified; 29% were African American, 24% Latino and 30% white. The majority (71%) indicated being on antiretroviral treatment, and most were taking a protease inhibitor/nucleoside reverse transcriptase inhibitor combination. African American men in New York City were less likely to be on treatment. Among those on treatment (n = 322), 51% reported at least one day in which they had missed a dose of their medication and the mean number of days in which a dose was missed (in the past 30 days) was 1.72. Multivariate analyses indicated that avoidant coping, frequency of drinking alcohol and difficulty in communicating with sex partners about HIV were related to days of missed doses, suggesting the need or desire to escape from the reality of life with HIV as a potential explanation for poor adherence.
作为“血清阳性城市男性研究”的一部分，收集了有关艾滋病毒抗逆转录病毒治疗方案、获得治疗和医疗护理以及药物依从性的数据，该研究是一项针对男同性恋艾滋病毒阳性者的形成性研究。参与者（N = 456）从艾滋病服务组织、主流同性恋场所和公共/商业性环境中招募。样本中94%为同性恋或双性恋者；29%为非裔美国人，24%为拉丁裔，30%为白人。大多数人（71%）表示正在接受抗逆转录病毒治疗，且大多数人正在服用蛋白酶抑制剂/核苷类逆转录酶抑制剂组合药物。纽约市的非裔美国男性接受治疗的可能性较小。在接受治疗的人群中（n = 322），51%的人报告至少有一天漏服了药物，过去30天漏服药物的平均天数为1.72天。多变量分析表明，回避应对、饮酒频率以及与性伴侣交流艾滋病毒相关问题的困难程度与漏服药物的天数有关，这表明逃避感染艾滋病毒后的生活现实的需求或愿望可能是依从性差的一个潜在原因。
