van der Gaag Marijn, Debets Alfons J M, Hoekstra Rolf F
Laboratory of Genetics, Department of Plant Sciences, Wageningen University, Arboretumlaan 4, 6703 BD Wageningen, The Netherlands.
Genetica. 2003 Jan;117(1):59-65. doi: 10.1023/a:1022364632611.
Fungi in which the haploid nuclei resulting from meiosis are linearly arranged in asci provide unique opportunities to analyse abnormal segregation. Any meiotic drive system in such fungi will be observed in a cross between a driving and a sensitive strain as spore killing: the degeneration of half the ascospores in a certain proportion of the asci. In a sample of some 100 strains isolated from a single natural population we have discovered at least six different meiotic drive elements (van der Gaag et al., 2000). Here we report results of research that was aimed at elucidating a possible correlation between meiotic drive and vegetative incompatibility in eight different Spore killer strains from this population. We show that there is a strong correlation between these two phenotypes, although the precise genetic nature of the correlation is not yet clear. We discuss the implications of our results for the understanding of the population genetics of meiotic drive in Podospora.
减数分裂产生的单倍体细胞核在子囊中呈线性排列的真菌，为分析异常分离提供了独特的机会。在这种真菌中，任何减数分裂驱动系统都将在一个驱动菌株和一个敏感菌株的杂交中作为孢子杀伤现象被观察到：在一定比例的子囊中，一半的子囊孢子会退化。在从单一自然群体中分离出的约100个菌株样本中，我们已经发现了至少六种不同的减数分裂驱动元件（范德加格等人，2000年）。在此，我们报告了一项研究结果，该研究旨在阐明来自该群体的八个不同孢子杀伤菌株中减数分裂驱动与营养体不亲和性之间可能存在的相关性。我们表明这两种表型之间存在很强的相关性，尽管这种相关性的确切遗传本质尚不清楚。我们讨论了我们的结果对于理解波氏粪壳菌减数分裂驱动群体遗传学的意义。
