Spierings Egilius L H
Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Headache. 2003 Apr;43(4):410-4. doi: 10.1046/j.1526-4610.2003.03079.x.
A patient developed severe, continuous, unilateral headache that was "vascular" in nature, following cervical sympathectomy.
To determine the changes in cranial blood flow in the cat following lesioning and stimulation of the cervical sympathetic nerve.
Carotid blood flow was determined by electromagnetic flowmetry and its tissue distribution by intra-arterial injection of 15-microm radioactive microspheres.
Following sympathetic lesioning, an increase in carotid blood flow was observed and reversed with stimulation. The distribution of carotid blood flow changed for the brain only, maintaining relatively constant tissue perfusion.
An increase in cerebral blood flow could not have accounted for the sympathectomy-induced headache. Dilation of major cerebral arteries and cranial noncerebral vasodilation probably constitutes its mechanism.
一名患者在进行颈交感神经切除术后出现严重、持续性单侧头痛，性质为“血管性”。
确定猫的颈交感神经损伤和刺激后颅血流量的变化。
通过电磁流量计测定颈动脉血流量，并通过动脉内注射15微米放射性微球确定其组织分布。
交感神经损伤后，观察到颈动脉血流量增加，刺激后逆转。仅大脑的颈动脉血流分布发生变化，组织灌注保持相对恒定。
脑血流量增加不能解释交感神经切除术后的头痛。大脑主要动脉的扩张和颅非脑血管扩张可能构成其机制。
