McNelis John, Marini Corrado P, Simms H Hank
Department of Surgery, Long Island Jewish Medical Center, Northshore-Long Island Jewish Health Systems, Albert Einstein College of Medicine, New Hyde Park, New York 11040, USA.
Curr Opin Crit Care. 2003 Apr;9(2):133-6. doi: 10.1097/00075198-200304000-00009.
Abdominal compartment syndrome (ACS) is the end result of sustained, uncorrected intraabdominal hypertension. In clinical and laboratory settings, ACS has been shown to adversely affect all vital organ systems. Although early descriptions emanated from the trauma literature, ACS is now encountered in all intensive care unit populations. In this review, we examine the literature and identify factors that may predict the onset of ACS.
The pathogenesis of ACS remains unclear, and few studies have sought to identify predictive clinical variables. Peak airway pressure and net 24-hour fluid gradient are the only variables that have been identified in the available literature as predictive of ACS development in controlled studies.
The earlier recognition of predictive variables and identification of patients at higher risk will hopefully lead to recognition and avoidance of the sequelae and increased mortality rate associated with ACS.
腹腔间隔室综合征（ACS）是持续性、未纠正的腹腔内高压的最终结果。在临床和实验室环境中，ACS已被证明会对所有重要器官系统产生不利影响。尽管早期描述源于创伤文献，但现在在所有重症监护病房人群中都能遇到ACS。在本综述中，我们研究了相关文献并确定了可能预测ACS发病的因素。
ACS的发病机制仍不清楚，很少有研究试图确定预测性临床变量。在现有文献中，峰值气道压力和24小时净液体梯度是在对照研究中确定的仅有的可预测ACS发生的变量。
尽早识别预测变量并确定高危患者，有望实现对ACS相关后遗症的识别与避免，并降低与之相关的死亡率。
