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[非典型勒里什综合征]

[Atypical Leriche syndrome].

作者信息

Bresan V, Irlbacher K, Bittner R, Meyer R, Dietz R, Möckel M

机构信息

Charité, Campus Virchow-Klinikum, Medizinische Klinik mit Schwerpunkt Kardiologie, Augustenburger Platz 1, 13353 Berlin, Germany.

出版信息

Z Kardiol. 2003 Mar;92(3):260-6. doi: 10.1007/s00392-003-0896-5.

Abstract

A 73-year old woman presented with mild paraparesis and hypesthesia of the legs. Furthermore, she complained dizziness, fainting and dyspnea. There was a history of peripheral artery disease, diabetes mellitus, arterial hypertension and chronic atrial fibrillation. Five years ago she had breast cancer with removal of the left mamma and additional radiation therapy. Cardiac catheterization at that time demonstrated no significant coronary stenoses. A contrast-enhanced CT-scan excluded lumbal spinal metastases. Instead, a subtotal occlusion of the abdominal aorta was noticed, but was initially interpreted as a chronic thrombosis because there were no typical symptoms and only moderate pain. About 24 hours later the patient developed an acute ischemic syndrome of the legs with progressive paraparesis, cold and pale legs in combination with acidosis and hyperventilation. Color-coded duplex ultrasound showed only a small turbulent flow in the ilial arteries, highly suspicious of a complete occlusion of the distal aorta. Angiography revealed an acute total occlusion of the infrarenal aorta without collaterals. During surgical intervention, complete obstruction of the abdominal aorta above the bifurcation was confirmed. Subsequent embolectomy was performed and an embolus consisting of several layers of different age was extracted. After successful surgical intervention with subsequent clinical improvement, the patient's clinical condition deteriorated a few day later. She died on day 9 after surgery from a complete ischemia of the small intestine and the colon ascendens.

摘要

一名73岁女性因双下肢轻度轻瘫和感觉减退就诊。此外,她还主诉头晕、昏厥和呼吸困难。既往有外周动脉疾病、糖尿病、动脉高血压和慢性心房颤动病史。5年前她患乳腺癌,接受了左侧乳房切除及额外的放射治疗。当时的心脏导管检查显示无明显冠状动脉狭窄。增强CT扫描排除了腰椎脊髓转移瘤。相反,发现腹主动脉次全闭塞,但最初被解释为慢性血栓形成,因为没有典型症状,仅有中度疼痛。约24小时后,患者出现下肢急性缺血综合征,伴有进行性轻瘫、下肢冰冷苍白,同时伴有酸中毒和通气过度。彩色编码双功超声显示髂动脉仅有少量湍流,高度怀疑腹主动脉远端完全闭塞。血管造影显示肾下腹主动脉急性完全闭塞且无侧支循环。手术干预期间,证实腹主动脉分叉上方完全阻塞。随后进行了栓子切除术,取出了一个由几层不同时期成分组成的栓子。手术成功且临床症状随后改善,但几天后患者的临床状况恶化。她在术后第9天死于小肠和升结肠完全缺血。

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