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运动性呼吸困难作为肾下腹主动脉闭塞性疾病的一种症状。

Exertional dyspnea as a symptom of infrarenal aortic occlusive disease.

作者信息

Schott Stacey L, Carreiro Fernanda Porto, Harkness James R, Malas Mahmoud B, Sozio Stephen M, Zakaria Sammy

机构信息

Departments of Medicine (Drs. Harkness, Porto Carreiro, Schott, Sozio, and Zakaria) and Vascular and Endovascular Surgery (Dr. Malas), Johns Hopkins University School of Medicine, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224.

出版信息

Tex Heart Inst J. 2014 Jun 1;41(3):316-8. doi: 10.14503/THIJ-13-3301. eCollection 2014 Jun.

Abstract

Advanced atherosclerosis of the aorta can cause severe ischemia in the kidneys, refractory hypertension, and claudication. However, no previous reports have clearly associated infrarenal aortic stenosis with shortness of breath. A 77-year-old woman with hypertension and hyperlipidemia presented with exertional dyspnea. Despite extensive testing and observation, no apparent cause for this patient's dyspnea was found. Images revealed severe infrarenal aortic stenosis. After the patient underwent stenting of the aortic occlusion, she had immediate symptomatic improvement and complete resolution of her dyspnea within one month. Twelve months after vascular intervention, the patient remained asymptomatic. In view of the distinct and lasting elimination of dyspnea after angioplasty and stenting of a nearly occluded infrarenal aortic lesion, we hypothesize that infrarenal aortic stenosis might be a treatable cause of exertional dyspnea. Clinicians should consider infrarenal aortic stenosis as a possible cause of dyspnea. Treatment of the stenosis might relieve symptoms.

摘要

主动脉严重动脉粥样硬化可导致肾脏严重缺血、顽固性高血压和跛行。然而,既往尚无明确报告表明肾下主动脉狭窄与呼吸急促有关。一名患有高血压和高脂血症的77岁女性出现劳力性呼吸困难。尽管进行了广泛的检查和观察,但未发现该患者呼吸困难的明显原因。影像学检查显示严重的肾下主动脉狭窄。患者接受主动脉闭塞支架置入术后,症状立即改善,呼吸困难在1个月内完全缓解。血管介入治疗12个月后,患者仍无症状。鉴于对几乎闭塞的肾下主动脉病变进行血管成形术和支架置入术后,呼吸困难明显且持久消除,我们推测肾下主动脉狭窄可能是劳力性呼吸困难的一个可治疗病因。临床医生应将肾下主动脉狭窄视为呼吸困难的可能病因。对狭窄进行治疗可能会缓解症状。

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