Werner Jochen A, Dünne Anja A, Myers Jeffrey N
Department of Otolaryngology, Head and Neck Surgery, Philipps University Marburg, Deutschhausstr. 3, 35037 Marburg, Germany.
Head Neck. 2003 Apr;25(4):322-32. doi: 10.1002/hed.10257.
Although there is a significant understanding of the vascular anatomy of the upper aerodigestive tract (UADT), there is less detailed knowledge of the architecture and drainage patterns of the lymphatic system. Detailed knowledge of the lymphatic system is critical for understanding the role of sentinal node identification in the management of different cancers.
We have combined microscopic techniques with in vivo and in vitro lymphographic studies to survey the architecture and drainage patterns of the lymphatic system of the UADT in 850 organ specimens.
These studies show an interaction of superficial and deep lymphatic networks that vary in density but have a constant distribution characterized by predictable patterns of lymph drainage into the regional lymph nodes.
Detailed knowledge of the lymphatic system of the UADT contributes to a better understanding of the patterns of metastatic spread of carcinomas of the UADT and provides a strong rationale for the practice of sentinel node identification in the management of these tumors.
尽管对上呼吸道消化道（UADT）的血管解剖已有相当的了解，但对淋巴系统的结构和引流模式的详细知识却较少。淋巴系统的详细知识对于理解前哨淋巴结识别在不同癌症管理中的作用至关重要。
我们将显微镜技术与体内和体外淋巴造影研究相结合，对850个器官标本中的UADT淋巴系统的结构和引流模式进行了调查。
这些研究表明，浅表和深部淋巴网络相互作用，其密度各不相同，但具有恒定的分布，其特征是淋巴引流至区域淋巴结的模式可预测。
UADT淋巴系统的详细知识有助于更好地理解UADT癌的转移扩散模式，并为在这些肿瘤的管理中进行前哨淋巴结识别提供了有力的理论依据。
