Bai Nian-yue, Guo Qu-lian, Liu Yao
Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China.
Hunan Yi Ke Da Xue Xue Bao. 2002 Dec 28;27(6):539-41.
To compare the anaesthetic effect and hemodynamic changes between the continuous spinal anaesthesia(CSA) and combined spinal-epidural anaesthesia (CSEA) in patients for uterectomy.
Sixty patients undergoing uterectomy were randomly divided into two groups: CSA group and CSEA group. Spinal anesthesia was performed at L2-3 interspace. An initial subarachnoid bolus of 0.5% hyperbaric bupivacaine 2 ml was injected in the CSA group; if analgesia did not reach T8, supplemental bupivacaine was injected by titrate incremental doses. In the CSEA group, epidural anesthesia was performed at T12-L1 with a catheter inserted into the epidural space for anesthesia maintenance, and then 0.5% hyperbaric bupivacaine 3 ml was injected to the subarachnoid at L2-3. The levels and times of sensory and motor block and hemodynamic changes were measured and analysed.
The anesthetic dosage of the CSA group was smaller than that of the CSEA group (group P < 0.05). The times of sensory block to T8 or the maximal level and motor block were more rapid in the CSEA group than those of the CSA group (P < 0.05). Mean arterial pressure (MAP), which decreased significantly, was related with the baseline in the two groups; the time was 15 min and 25 min in the CSEA group and CSA group respectively (P < 0.05). There was no difference in the maximum decline of MAP in the two groups (P < 0.01).
CSA is a safe technique of spinal anesthesia with small anesthetic dosages, more reliable and hemodynamically stable in patients for uterectomy.
比较连续蛛网膜下腔麻醉(CSA)与腰麻-硬膜外联合麻醉(CSEA)用于子宫切除术患者的麻醉效果及血流动力学变化。
将60例行子宫切除术的患者随机分为两组:CSA组和CSEA组。于L2-3间隙行脊髓麻醉。CSA组蛛网膜下腔首剂注入0.5%重比重布比卡因2 ml;若镇痛平面未达T8,则追加布比卡因进行滴定增量给药。CSEA组于T12-L1行硬膜外麻醉并置入导管用于维持麻醉,然后于L2-3向蛛网膜下腔注入0.5%重比重布比卡因3 ml。测量并分析感觉和运动阻滞的平面及时间以及血流动力学变化。
CSA组麻醉用药量小于CSEA组(组间P<0.05)。CSEA组感觉阻滞至T8的时间、最大平面及运动阻滞均比CSA组更快(P<0.05)。两组平均动脉压(MAP)均显著下降,且与基线相关;CSEA组和CSA组分别在15分钟和25分钟时出现下降(P<0.05)。两组MAP最大降幅无差异(P<0.01)。
CSA是一种安全的脊髓麻醉技术,用于子宫切除术患者时麻醉用药量小、更可靠且血流动力学稳定。