Il'chenko A A, Orlova Iu N
Central Scientific Research Institute of Gastroenterology, Moscow.
Eksp Klin Gastroenterol. 2003(1):46-50, 182.
23 patients with gall-bladder cholesterosis associated with cholesterol gallstones were treated with ursodeoxycholic acid preparations. A regression of cholesterol polyps was recorded in 56.5% against the background of treatment, and complete or partial dissolution of gallstones was observed in 87%. The efficiency of dissolution of cholesterol polyps and stones in the gall-bladder went up along with the extension of the therapy terms, reaching its maximum by 7-9 months of treatment. The dissolution rates were higher for gallstones than for cholesterol polyps. The volume of bile being secreted increased, and the gall-bladder contractile function improved in the course of treatment.
23例患有胆囊胆固醇沉着症并伴有胆固醇结石的患者接受了熊去氧胆酸制剂治疗。治疗期间，56.5%的患者胆固醇息肉出现消退，87%的患者胆结石出现完全或部分溶解。随着治疗时间延长，胆囊内胆固醇息肉和结石的溶解效率提高，治疗7至9个月时达到最高。胆结石的溶解率高于胆固醇息肉。治疗过程中，胆汁分泌量增加，胆囊收缩功能改善。
