Domaev Iu A
Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(2):224-8.
EEG studies of 112 patients in different stages of the uric (Kashin-Beck) disease revealed pathological shifts in the brain biopotentials, which were beyond the aging changes. Analysis of the EEG tracing demonstrated that the index of alpha-activity along with a progressive severity of the disease, especially in the 2nd and 3d stage, was statistically less, while the per cent of pathological forms of potentials increased. In a rhythmic photostimulation there were disorders in the brain reactivity. These data point to a diffuse lesion of the brain. A correlation between clinical, EEG and other studies permit to consider the uric disease as a chronic disorder leading to an early aging of the organism.
对112例处于不同阶段的大骨节病患者进行的脑电图研究显示，大脑生物电位出现了病理性变化，这种变化超出了衰老改变的范畴。脑电图描记分析表明，随着疾病严重程度的逐渐增加，尤其是在第二和第三阶段，α波活动指数在统计学上降低，而电位病理性形式的百分比增加。在节律性光刺激中，大脑反应性出现紊乱。这些数据表明大脑存在弥漫性病变。临床、脑电图及其他研究之间的相关性使得人们可以将大骨节病视为一种导致机体过早衰老的慢性疾病。
