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颅脑创伤后血清和脑脊液中的抗脑抗体

[Anti-brain antibodies in serum and cerebrospinal fluid following cranio-cerebral trauma].

作者信息

Detlav I E

出版信息

Zh Nevropatol Psikhiatr Im S S Korsakova. 1976;76(3):344-8.

PMID:1266503
Abstract

The author evaluated the precipitating antibrain antibodies by the Hoigne' method in the blood serum of 292 patients and in the CSF of 194 patients with acute brain traumas. Accordingly 52 and 21 patients were studied in the remote period. Antibodies were revealed more frequently and for a longer period of time following severe damages and less frequently in mild forms. They could also be revealed in patients with residual symptoms of brain trauma. Antibodies were revealed in the CSF earlier, more frequently and for a longer period of time than in the blood sera. These data speak in favour of a probable local formation of antibrain antibodies.

摘要

作者采用霍伊涅氏方法对292例急性脑外伤患者的血清及194例患者的脑脊液中的抗脑抗体进行了评估。相应地,对52例和21例患者进行了远期研究。严重损伤后抗体出现得更频繁且持续时间更长,轻度损伤时则较少出现。在有脑外伤残留症状的患者中也能检测到抗体。脑脊液中抗体出现的时间更早、频率更高且持续时间更长,高于血清。这些数据表明抗脑抗体可能在局部形成。

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