Zhang Jie, Tsai Jang-Zern, Cao Hong, Chen Yi, Will James A, Vorperian Vicken R, Webster John G
Department of Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI 53706, USA.
IEEE Trans Biomed Eng. 2003 Feb;50(2):218-23. doi: 10.1109/TBME.2002.807647.
Radio-frequency (RF) cardiac catheter ablation has been very successful for treating some cardiac arrhythmias, however, the success rate for ventricular tachycardias is still not satisfactory. Some existing methods for developing deeper lesions include active cooling of the electrode and modifying the electrode shape. We propose a method of noncontact ablation, to solve this problem. We apply 120 W of power through an 8-mm electrode for a 120-s duration, with distances from 0 to 3 mm between electrode and myocardium, to create lesions in myocardium. We apply flow rates of 1, 3, and 5 L/min to determine their effect. Results show that with an optimal distance from 0.5 to 1.5 mm between electrode and myocardium, we increase lesion depth from 7.5 mm for contact ablation to 9.5 mm for noncontact ablation. For different flow rates, the optimal distance various. The effect of flow rate is not obvious. Higher flow rate does not lead to a deeper lesion.
射频（RF）心脏导管消融术在治疗某些心律失常方面非常成功，然而，室性心动过速的成功率仍然不尽人意。一些现有的形成更深损伤的方法包括电极的主动冷却和改变电极形状。我们提出一种非接触消融方法来解决这个问题。我们通过一个8毫米的电极施加120瓦的功率，持续120秒，电极与心肌之间的距离为0至3毫米，以在心肌中形成损伤。我们施加1、3和5升/分钟的流速来确定它们的效果。结果表明，电极与心肌之间的最佳距离为0.5至1.5毫米时，我们将接触消融的损伤深度从7.5毫米增加到非接触消融的9.5毫米。对于不同的流速，最佳距离各不相同。流速的影响并不明显。较高的流速并不会导致更深的损伤。
