Jensen I
Acta Neurol Scand. 1976 Feb;53(2):103-18. doi: 10.1111/j.1600-0404.1976.tb04329.x.
Seventy-four patients with temporal lobe epilepsy, resistant to medication, who in 1960-1969 underwent unilateral temporal lobe resection at Rigshospitalet, Copenhagen. In only 12 patients was no etiological factor found. In three-quarters of the patients a peri- or postnatal injury was the suspected etiology of the epilepsy; and in one-third, a history of complications in the actual and/or abnormal outcome of a previous pregnancy was recorded. Only seven patients had experienced febrile convulsions. Patients with certain combinations of etiological factors, including encephalitis, have a poor prognosis regarding relief from seizures. Patients in whom an abnormal outcome of the mother's previous pregnancies is recorded have a poor prognosis as regards psychiatric normalization. Apart from this no correlation has been found between the surgical results and the numbers or types of the various etiological factors.
74例颞叶癫痫患者,药物治疗无效,于1960年至1969年在哥本哈根的里格霍斯皮塔尔接受了单侧颞叶切除术。仅12例患者未发现病因。四分之三的患者癫痫的疑似病因是围产期或产后损伤;三分之一的患者有既往妊娠实际和/或异常结局的并发症史。只有7例患者曾有高热惊厥。具有某些病因组合(包括脑炎)的患者癫痫发作缓解的预后较差。记录有母亲既往妊娠异常结局的患者在精神状态恢复正常方面预后较差。除此之外,未发现手术结果与各种病因的数量或类型之间存在相关性。