Gladkiĭ A P
Arkh Anat Gistol Embriol. 1975 Aug;69(8):101-9.
The paper summarizes the data of the author and his co-workers on regulation of the musculature of vessels, digestive tract, uterus, ureters and urinary bladder. The smooth muscle cells have different degrees of differentiation. The muscular tissue of the vessels is most differentiated. The uterus musculature is very plastical. After injury mature myocytes are the first to undergo destruction. The intermedial substance is more stable. Myoblasts, young elements of the fibroblast row and the subendothelial layer cells are the origin of muscular regeneration. Figures of mitosis and amitosis are noted. Mature myocytes and intercellular substance are formed in the process of differentiation of the regeneration. The content of RNP in the regeneration cells is high, but in the process of differentiation of its elements it becomes lower. The DNP level has inconsiderable fluctuations. In early experiments PAS-positive substances are revealed in greater degree than in later ones. The content of acid mucopolysaccharides decreases in the process of fibrillogenesis. In all internal organs under study the muscular tissue regenerated. The degree of differentiation, severity of the lesion and functional peculiarities of the organ determine the completeness of the tissue reparation. The musculature of the intestinal tract and vessels regenerates more completely. Mighty layers of connective tissue with de novo formed blood vessels are disposed among the bundles of the repaired muscular tissue of the uterus and urine bladder wall. Simultaneously a part of regeneration cells are destroyed. These are two sides of a single process of development.
本文总结了作者及其同事关于血管、消化道、子宫、输尿管和膀胱肌肉组织调节的数据。平滑肌细胞具有不同程度的分化。血管的肌肉组织分化程度最高。子宫肌肉组织非常具有可塑性。损伤后,成熟的肌细胞最先受到破坏。中间物质更稳定。成肌细胞、成纤维细胞系的年轻成分和内皮下层细胞是肌肉再生的起源。观察到有丝分裂和无丝分裂的现象。在再生分化过程中形成成熟的肌细胞和细胞间物质。再生细胞中核糖核蛋白(RNP)的含量很高,但在其成分分化过程中会降低。脱氧核糖核蛋白(DNP)水平波动不大。在早期实验中,过碘酸雪夫反应(PAS)阳性物质的显示程度比后期更高。在纤维形成过程中酸性粘多糖的含量降低。在所研究的所有内脏器官中,肌肉组织都能再生。分化程度、病变严重程度和器官的功能特性决定了组织修复的完整性。肠道和血管的肌肉组织再生更完全。在子宫和膀胱壁修复后的肌肉组织束之间分布着带有新生血管的强大结缔组织层。同时,一部分再生细胞被破坏。这是一个单一发育过程的两个方面。