Gruneberg Ulrike, Nigg Erich A
Max-Planck-Institute for Biochemistry, Am Klopferspitz 18a, 82152 Martinsried, Germany.
Trends Cell Biol. 2003 Apr;13(4):159-62. doi: 10.1016/s0962-8924(03)00034-5.
A novel mechanism, centered on the Polo-like kinase Plo1p and Dma1p - a protein with a RING finger and an FHA-domain - prevents cytokinesis as long as the spindle checkpoint is active.
一种以类Polo激酶Plo1p和Dma1p(一种具有泛素连接酶环指结构域和叉头相关结构域的蛋白质)为核心的新机制,只要纺锤体检查点处于激活状态,就会阻止胞质分裂。