Dennis D T, Partono F, Atmosoedjono P S, Saroso J S
Am J Trop Med Hyg. 1976 Nov;25(6):797-802. doi: 10.4269/ajtmh.1976.25.797.
The epidemiology of Timor filariasis was observed during a clinical and parasitologic survey of persons living in a remote village on the island of Flores, Southeast Indonesia. Infection and disease was distributed evenly throughout the community, which was in accord with the breeding and feeding habits of the only identified vector, Anopheles barbirostris. Although micfofilaremia rates appeared independent of host variables of age and sexes and sex, symptoms of disease were greater among males than females, and in both sexes disease rates more than doubled between the first and second decades of life. Symptoms included recurring episodes of inguinal and femoral lymphadenitis with retrograde lymphangitis and fever, abscesses of lymph glands or vessels along the path of the great sapheneous vein and its mae highest yet reported for the Timor filaria; it is a virulent parasite causing serious ill-health among the inhabitants of eastern Flores.
在对印度尼西亚东南部弗洛勒斯岛一个偏远村庄居民进行的临床和寄生虫学调查中,观察了帝汶丝虫病的流行病学情况。感染和疾病在整个社区中分布均匀,这与唯一已确定的传播媒介——须喙按蚊的繁殖和觅食习性相符。尽管微丝蚴血症率似乎与年龄和性别等宿主变量无关,但男性的疾病症状比女性更严重,且在两个性别中,疾病发生率在生命的第一个十年到第二个十年之间都增加了一倍多。症状包括腹股沟和股部淋巴结炎反复发作并伴有逆行性淋巴管炎和发热、大隐静脉及其分支沿线的淋巴结或血管脓肿,这是帝汶丝虫迄今报告的最高发病率;它是一种毒性很强的寄生虫,给弗洛勒斯岛东部的居民带来严重健康问题。