Menninger R P, Baker C H
Am J Physiol. 1976 Mar;230(3):797-803. doi: 10.1152/ajplegacy.1976.230.3.797.
Canine forelimbs were vascularly isolated and perfused at either constant inflow or constant inflow pressure. A comparison of the effects of electrical stimulation of hypothalamic pressor areas and brachial nerves was made on several vascular parameters. During constant pressure perfusion, forelimb resistance increased and total forelimb volume decreased. Additionally active vascular volumes measured with 131I-labeled albumin and 51Cr-labeled red cells decreased significantly. Capillary diffusion capacity product calculated from extraction of 86RbCl also decreased significantly as did the capillary filtration coefficient (CFC). The only significant differences between hypothalamic and brachial nerve stimulation were noted in the larger decreases in active volumes and CFC during the latter stimulations.
犬的前肢进行血管分离，并以恒定流入量或恒定流入压力进行灌注。比较了下丘脑升压区和臂神经电刺激对几个血管参数的影响。在恒压灌注期间，前肢阻力增加，前肢总体积减小。此外，用131I标记的白蛋白和51Cr标记的红细胞测量的有效血管容积显著降低。由86RbCl提取量计算出的毛细血管扩散容量乘积也显著降低，毛细血管滤过系数（CFC）也是如此。下丘脑刺激和臂神经刺激之间唯一显著的差异在于，后者刺激期间有效容积和CFC的下降幅度更大。
