Satoh Nori
Department of Zoology, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502, Japan.
Nat Rev Genet. 2003 Apr;4(4):285-95. doi: 10.1038/nrg1042.
Evolution is of interest not only to developmental biology but also to genetics and genomics. We are witnessing a new era in which evolution, development, genetics and genomics are merging to form a new discipline, a good example of which is the study of the origin and evolution of the chordates. Recent studies on the formation of the notochord and the dorsal neural tube in the increasingly famous Ciona intestinalis tadpole larva, and the availability of its draft genome, show how the combination of comparative molecular development and evolutionary genomics might help us to better understand our chordate ancestor.
进化不仅对发育生物学有意义,对遗传学和基因组学也同样重要。我们正在见证一个新时代的到来,在这个时代,进化、发育、遗传学和基因组学正在融合形成一门新学科,其中一个很好的例子就是脊索动物起源与进化的研究。最近对越来越著名的玻璃海鞘蝌蚪幼虫中脊索和背神经管形成的研究,以及其基因组草图的可得性,表明了比较分子发育学和进化基因组学的结合如何能够帮助我们更好地理解我们的脊索动物祖先。