Kim Young-Hoo, Oh S-H, Kim J-S, Koo K-H
The Joint Replacement Center of Korea, Seoul, Korea.
J Bone Joint Surg Am. 2003 Apr;85(4):675-81. doi: 10.2106/00004623-200304000-00014.
The rate of failure of primary total hip arthroplasty in patients with osteonecrosis of the femoral head is higher than that in patients with osteoarthritis. The purpose of this prospective study was to document the clinical and radiographic results of arthroplasty with so-called third-generation cementing and the results of second-generation cementless total hip arthroplasty in ninety-eight consecutive patients with osteonecrosis of the femoral head.
Fifty patients who had had simultaneous bilateral total hip arthroplasty with a cemented stem in one hip and a cementless stem in the other and forty-eight patients who had had a unilateral total hip arthroplasty with a cementless stem were included in the study. A cementless acetabular component was used in all hips. The presumed cause of the osteonecrosis was ethanol abuse in fifty-seven patients, unknown in twenty-seven, fracture of the femoral neck in nine, and steroid use in five. There were eighty men and eighteen women. The mean age at the time of the arthroplasty was 47.3 years (range, twenty-six to fifty-eight years). Clinical and radiographic evaluations were performed preoperatively; at six weeks; at three, six, and twelve months; and yearly thereafter. The average duration of follow-up was 9.3 years.
The average Harris hip scores in the group treated with unilateral arthroplasty (97 points) and the group treated with bilateral arthroplasty (94 points) were similar at the time of final follow-up. They were also similar between the group treated with cement (mean, 96 points) and that treated without cement (95 points). No component had aseptic loosening in either group. In one hip, a cemented femoral stem (2%) and a cementless cup were revised because of infection. Two cementless stems (2%) were revised because of fracture of the proximal part of the femur with loosening of the stem. Annual wear of the polyethylene liner averaged 0.22 mm in the group treated with cement (a zirconia head) and 0.14 mm in the group treated without cement (a cobalt-chromium head). The prevalence of osteolysis in zones 1 and 7 of the femur was 16% in the group treated with cement and 24% in the group treated without cement.
Advancements in surgical technique and better designs have greatly improved the long-term survival of cemented and cementless implants in young patients with osteonecrosis of the femoral head. Although there was no aseptic loosening of the components, a high rate of linear wear of the polyethylene liner and a high rate of osteolysis in these high-risk young patients remain challenging problems.
股骨头坏死患者初次全髋关节置换术的失败率高于骨关节炎患者。这项前瞻性研究的目的是记录98例连续的股骨头坏死患者采用所谓第三代骨水泥技术进行关节置换术的临床和影像学结果,以及第二代非骨水泥型全髋关节置换术的结果。
50例患者一侧髋关节采用骨水泥型假体进行双侧全髋关节置换,另一侧采用非骨水泥型假体;48例患者采用非骨水泥型假体进行单侧全髋关节置换。所有髋关节均使用非骨水泥型髋臼组件。57例患者股骨头坏死的推测病因是乙醇滥用,27例病因不明,9例为股骨颈骨折,5例为使用类固醇。患者中男性80例,女性18例。关节置换时的平均年龄为47.3岁(范围26至58岁)。术前、术后6周、3个月、6个月、12个月以及此后每年进行临床和影像学评估。平均随访时间为9.3年。
在最终随访时,单侧关节置换组(97分)和双侧关节置换组(94分)的平均Harris髋关节评分相似。骨水泥组(平均96分)和非骨水泥组(95分)的评分也相似。两组均无假体无菌性松动。1例髋关节(2%)因感染对骨水泥型股骨柄和非骨水泥型髋臼杯进行了翻修。2例非骨水泥型股骨柄(2%)因股骨近端骨折伴柄松动而进行了翻修。骨水泥组(使用氧化锆股骨头)聚乙烯内衬的年磨损平均为0.22 mm,非骨水泥组(使用钴铬合金股骨头)为0.14 mm。股骨1区和7区骨溶解的发生率在骨水泥组为16%,在非骨水泥组为24%。
手术技术的进步和更好的设计极大地提高了股骨头坏死年轻患者中骨水泥型和非骨水泥型植入物的长期生存率。尽管假体无无菌性松动,但在这些高危年轻患者中,聚乙烯内衬的高线性磨损率和高骨溶解率仍然是具有挑战性的问题。