Blanco A, Andión R, Solís P, Blanco S, Sánchez Villares E
An Esp Pediatr. 1976 Jan-Feb;9(1):48-52.
138 cases of viral hepatitis were selected among 27,000 pediatric clinical records corresponding to the years 1965-75. The clinical course of patients receiving corticosteroids during the acute phase was compared to that of the remaining patients, and an increased number of prolonged course cases was observed. At the same time, more frequent evolution to either aggressive forms or cirrhosis is suggested. Therefore, the authors discourage the use of corticosteroids in the treatment of common viral hepatitis.
在1965年至1975年期间的27000份儿科临床记录中,选取了138例病毒性肝炎病例。将急性期接受皮质类固醇治疗的患者的临床病程与其余患者的临床病程进行比较,观察到病程延长的病例数量增加。同时,提示发展为侵袭性形式或肝硬化的情况更频繁。因此,作者不主张在普通病毒性肝炎的治疗中使用皮质类固醇。