Piérard-Franchimont Claudine, Quatresooz Pascale, Piérard Gérald E
Department of Dermatopathology, University Medical Center of Liège, Belgium.
Dermatology. 2003;206(3):249-51. doi: 10.1159/000068898.
The precise pathomechanism of rosacea remains elusive. The disease commonly requires long-term treatments using topical or oral therapies.
This report presents incidental findings about the possible modulatory role of somatostatin in the outcome of rosacea.
Four patients presenting long-standing recalcitrant facial rosacea were treated with octreotide for diabetic retinopathy.
Rosacea improved rapidly and even cleared without any recurrence in 3 of the patients.
The beneficial effect might be attributed to inhibitory actions on the sebaceous gland, the neovascularization and/or on the inflammatory process.
酒渣鼻的确切发病机制仍不清楚。该病通常需要使用局部或口服疗法进行长期治疗。
本报告介绍了关于生长抑素在酒渣鼻病情转归中可能的调节作用的意外发现。
4例患有长期顽固性面部酒渣鼻的患者因糖尿病视网膜病变接受奥曲肽治疗。
3例患者的酒渣鼻迅速改善，甚至完全消退且无复发。
这种有益作用可能归因于对皮脂腺、新血管形成和/或炎症过程的抑制作用。
