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[用于人甲状旁腺激素放射免疫测定的豚鼠抗牛甲状旁腺激素抗血清的特性]

[Characteristics of guinea pig anti-bovine parathormone antiserum used in radioimmunologic determination of human parathormone].

作者信息

Mallet E, Brunelle P, Fillastre J P, Maitrot B, de Menibus C

出版信息

C R Seances Soc Biol Fil. 1975;169(1):213-7.

PMID:126732
Abstract

The cross-reaction for hPTH radioimmunoassay and the multiple forms of hPTH circulating, pose several problems in interpreting results. This communication reports a sensitive radioimmunoassay for hPTH utilising a guineapig antiserum which is reactive with the amino-terminal region retaining biological activity, and which cross-reacts completely with hPTH, indicating levels of hPTH expressed as bovine PTH equivalent that would be correct.

摘要

人甲状旁腺激素(hPTH)放射免疫测定中的交叉反应以及循环中hPTH的多种形式,在解释结果时带来了几个问题。本通讯报道了一种利用豚鼠抗血清的hPTH敏感放射免疫测定法,该抗血清与保留生物活性的氨基末端区域反应,并且与hPTH完全交叉反应,表明以牛PTH当量表示的hPTH水平将是正确的。

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