Kathula Satheesh K, Shah Ketan, Polenakovik Hari, Koduri Jhansi
Department of Medicine, Wright State University, Dayton, Ohio, USA.
Support Care Cancer. 2003 Apr;11(4):258-9. doi: 10.1007/s00520-002-0432-6. Epub 2003 Mar 1.
Neoplastic fever is relatively common in cancer patients. Naproxen is one of the most commonly used non-steroidal anti-inflammatory drugs for the treatment of neoplastic fever. Naproxen is associated with platelet dysfunction and gastrointestinal side effects. We substituted rofecoxib, a cyclooxygenase-II inhibitor, for naproxen in patients with a previous history of, or a newly diagnosed, neoplastic fever in whom naproxen was relatively contraindicated. In all patients the fever resolved completely without any side effects.
