保留皮肤的乳房切除术即刻重建及微小皮瓣保乳重建对肿瘤整形乳房手术结局的影响

Impact of skin-sparing mastectomy with immediate reconstruction and breast-sparing reconstruction with miniflaps on the outcomes of oncoplastic breast surgery.

作者信息

Gendy R K, Able J A, Rainsbury R M

机构信息

Breast Unit, Royal Hampshire County Hospital, Winchester S022 5DG, UK.

出版信息

Br J Surg. 2003 Apr;90(4):433-9. doi: 10.1002/bjs.4060.

Abstract

BACKGROUND

The aim of this study was to compare the outcomes of skin-sparing mastectomy (SSM) with immediate myocutaneous flap reconstruction and partial mastectomy with latissimus dorsi miniflap reconstruction (LDMF) for breast cancer.

METHODS

Some 106 disease-free patients (57 SSM, 49 LDMF) who had breast reconstruction between 1991 and 1999 participated in this retrospective review. The mean duration of follow-up was 42 (range 6-102) months. Measured outcomes included surgical complications, functional disability, cosmetic result and psychological morbidity.

RESULTS

SSM outcomes were less favourable than LDMF outcomes with regard to postoperative complications (14 versus 8 per cent), further surgical interventions (79 versus 12 per cent), nipple sensory loss (98 versus 2 per cent), restricted activities (73 versus 54 per cent) and cosmetic outcome by panel assessment. Anxiety about residual cancer and ease of breast self-examination were similar in both groups.

CONCLUSION

LDMF was associated with fewer adverse surgical and physical sequelae than SSM, without compromising local control or cosmetic outcome. Both operations were associated with low psychological morbidity.

摘要

背景

本研究旨在比较保留皮肤的乳房切除术(SSM)联合即刻肌皮瓣重建与部分乳房切除术联合背阔肌小皮瓣重建(LDMF)治疗乳腺癌的效果。

方法

1991年至1999年间接受乳房重建的106例无病患者(57例行SSM,49例行LDMF)参与了这项回顾性研究。平均随访时间为42(6 - 102)个月。测量的结果包括手术并发症、功能障碍、美容效果和心理疾病。

结果

在术后并发症(14%对8%)、进一步手术干预(79%对12%)、乳头感觉丧失(98%对2%)、活动受限(73%对54%)以及专家评估的美容效果方面,SSM的效果不如LDMF。两组患者对残留癌症的焦虑以及乳房自我检查的难易程度相似。

结论

与SSM相比,LDMF的手术和身体不良后遗症更少,且不影响局部控制或美容效果。两种手术的心理疾病发生率均较低。

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