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[通过R带标记鉴定人类癌细胞中观察到的染色体畸变]

[Identification of chromosome aberrations observed in human cancerous cells by labeling of R bands].

作者信息

Ayraud N

出版信息

C R Seances Soc Biol Fil. 1975;169(2):365-72.

PMID:126771
Abstract

A precise identification of chromosome abnormalities observed in cancerous human cells may be demonstrated by chromosome banding. The types of newly formed chromosomes seem to indicate the possibility of a correlation between chromosome rearrangements and regions of heterochromatin. The evolution of neoplastic cells would be due to a balance between an increase in the level of chromosome mutation and stable changes.

摘要

通过染色体显带可精确鉴定在人类癌细胞中观察到的染色体异常。新形成染色体的类型似乎表明染色体重排与异染色质区域之间存在关联的可能性。肿瘤细胞的进化将归因于染色体突变水平的增加与稳定变化之间的平衡。

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