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Clarion HiFocus电极外侧和内侧放置时的电诱发听觉脑干反应。

Electrically evoked auditory brain stem responses for lateral and medial placement of the Clarion HiFocus electrode.

作者信息

Firszt Jill B, Wackym Phillip A, Gaggl Wolfgang, Burg Linda S, Reeder Ruth M

机构信息

Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, USA.

出版信息

Ear Hear. 2003 Apr;24(2):184-90. doi: 10.1097/01.AUD.0000061230.58992.9A.

Abstract

OBJECTIVE

The purpose of this study was to compare the electrically evoked auditory brain stem response (EABR) for lateral and medial placement of the Clarion HiFocus cochlear implant electrode array via the electrode positioning system (EPS).

DESIGN

Twenty-five adult and pediatric cochlear implant recipients participated in the study. Intraoperatively recorded EABRs were evoked by stimuli via three intracochlear electrodes representing apical, medial, and basal locations, and responses were elicited before and after positioner insertion. Evoked potential measures of wave V amplitude and threshold were examined for statistical significance using ANOVA for repeated measures and Chi-Square methods.

RESULTS

For a given supra-threshold stimulus level, the increase in EABR wave V amplitude was significantly larger after EPS placement compared to before EPS placement for electrodes 1 (apical) and 13 (basal). Likewise, when the stimulus was decreased to obtain a minimal amplitude, the wave V threshold was significantly lower after EPS placement for electrodes 7 (medial) and 13. The number of measurements that showed decreased wave V threshold after EPS insertion was significantly dependent on intracochlear electrode location.

CONCLUSIONS

Placement of the Clarion Electrode Positioning System following HiFocus electrode insertion resulted in a reduction in the electrical current required to activate the auditory system. The effect of the EPS was greatest for the basal location, demonstrated by lower wave V thresholds and a larger percentage increase in wave V amplitude. The EABR reflected electrophysiologic changes relative to lateral-to-medial changes in intracochlear electrode position due to the EPS.

摘要

目的

本研究旨在通过电极定位系统(EPS)比较Clarion HiFocus人工耳蜗电极阵列外侧和内侧放置时的电诱发听觉脑干反应(EABR)。

设计

25名成人及儿童人工耳蜗植入受者参与了本研究。术中记录通过代表蜗顶、中间和基底位置的三个蜗内电极施加刺激所诱发的EABR,在插入定位器前后分别引出反应。使用重复测量方差分析和卡方方法检查V波振幅和阈值的诱发电位测量结果的统计学显著性。

结果

对于给定的阈上刺激水平,与EPS放置前相比,电极1(蜗顶)和电极13(基底)在EPS放置后EABR V波振幅的增加显著更大。同样,当降低刺激强度以获得最小振幅时,电极7(中间)和电极13在EPS放置后V波阈值显著更低。EPS插入后显示V波阈值降低的测量次数显著取决于蜗内电极位置。

结论

在HiFocus电极插入后放置Clarion电极定位系统可降低激活听觉系统所需的电流。EPS对基底位置的影响最大,表现为V波阈值更低以及V波振幅的百分比增加更大。EABR反映了由于EPS导致的蜗内电极位置从外侧到内侧变化所引起的电生理变化。

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