Friedel W, Chambers R G, Atkins J P
Arch Otolaryngol. 1976 May;102(5):286-90. doi: 10.1001/archotol.1976.00780100072009.
Pseudosarcoma of the pharynx and larynx has remained an enigma both to the pathologist and clinician since its original description by Lane in 1957. These lesions are usually polypoid growths that microscopically present very bizarre appearances beneath a squamous cell carcinoma. Eight cases of pseudosarcoma of the larynxand pharynx were observed. These occurred almost twice as often in males as females, with an average age of 56 years. Most were extralaryngeal lesions, and in all cases surgical excision was the primary therapeutic modality. A thorough review of the literature summarizes the clinical and pathologic characteristics of these lesions. There is strong clinical evidence against the traditional belief of the benign course of these lesions, and we recommend that they be treated aggresively like any other carcinoma of the head and neck.
自1957年莱恩首次描述以来，咽喉部假肉瘤一直让病理学家和临床医生感到困惑。这些病变通常呈息肉样生长，在显微镜下，其外观在鳞状细胞癌下方显得非常怪异。观察到8例咽喉部假肉瘤病例。男性发病几率几乎是女性的两倍，平均年龄为56岁。大多数为喉外病变，所有病例均以手术切除作为主要治疗方式。对文献进行全面回顾总结了这些病变的临床和病理特征。有强有力的临床证据反驳这些病变为良性病程的传统观点，我们建议像对待其他头颈癌一样积极治疗这些病变。
