Dhar Rajat, Duke Robert J, Sealey Brian J
Department of Clinical Neurological Sciences, London Health Sciences Center, The University of Western Ontario, London.
Can J Cardiol. 2003 Mar 15;19(3):295-6.
Loss of consciousness associated in some people with coughing is likely due to the hemodynamic changes induced by this exaggerated Valsalva manoeuvre. Cough syncope classically occurs in people with obstructive pulmonary disorders and it is unusual to find a specific correctable lesion precipitating it. A previously healthy man who developed tussive syncope in association with constrictive pericarditis and subsequently was cured by pericardiectomy is described. Although cough is a recognized feature of this cardiovascular condition, associated cough syncope has not previously been reported. However, the hemodynamic changes induced by constriction of cardiac filling understandably may further reduce cerebral perfusion during coughing. Not only does this case present a novel cause of this interesting syncopal syndrome, but it supports the basic pathophysiology thought to underlie it.
在一些人身上，意识丧失与咳嗽相关，这可能是由于这种夸张的瓦尔萨尔瓦动作引起的血流动力学变化所致。咳嗽性晕厥典型地发生在患有阻塞性肺部疾病的人群中，发现导致其发生的特定可纠正病变并不常见。本文描述了一名先前健康的男性，他因缩窄性心包炎出现咳嗽性晕厥，随后通过心包切除术治愈。尽管咳嗽是这种心血管疾病的一个公认特征，但此前尚未有相关咳嗽性晕厥的报道。然而，心脏充盈受限引起的血流动力学变化在咳嗽时可能会进一步减少脑灌注，这是可以理解的。这个病例不仅提出了这种有趣的晕厥综合征的一个新病因，而且支持了被认为是其基础的基本病理生理学。
