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[免疫原性肽新生物刺激辐射后血小板生成的恢复]

[Immunogenic peptide neogen stimulates postradiation recovery thrombopoiesis].

作者信息

Ziablitskiĭ V M, Semina O V, Semenets T N, Starosel'skaia A N, Romanovskaia V N, Mikhal'skaia T Iu, Poverennyĭ A M, Deĭgin V I

机构信息

Medical Radiology Research Centre, Russian Academy of Medical Sciences, Obninsk, 249036 Russia.

出版信息

Radiats Biol Radioecol. 2003 Jan-Feb;43(1):49-50.

PMID:12677657
Abstract

In experiments on mice F1 total exposed to gamma-irradiation at the 5.0 Gy, showed that a intraperitoneal injection neogen at the dose 10 micrograms/kg oue time at the day and night during the 8 days after irradiation results in recovery of the number blood platelets and time issue of blood from standard wound to normal level on the week by compare with irradiated control animals.

摘要

在对接受5.0戈瑞全身γ射线照射的F1代小鼠进行的实验中,结果显示,在照射后的8天里,每天早晚一次腹腔注射剂量为10微克/千克的新基因,与受照射的对照动物相比,可使血小板数量恢复正常,并使标准伤口的出血时间在一周内恢复到正常水平。

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Thrombopoietin protects mice from mortality and myelosuppression following high-dose irradiation: importance of time scheduling.血小板生成素可保护小鼠免受高剂量辐射后的死亡和骨髓抑制:时间安排的重要性。
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