Flikweert E R, Nugteren W A H, Groote A D
Afd. Algemene Heelkunde, Martini Ziekenhuis, Van Swietenlaan 4, 9728 NZ Groningen.
Ned Tijdschr Geneeskd. 2003 Mar 15;147(11):510-3.
In a 40-year-old woman with a swelling in the left lobe of the thyroid gland, fine needle aspiration cytology led to the suspicion of papillary thyroid carcinoma. Hemithyroidectomy with a frozen section examination followed. The frozen section was also suggestive of papillary carcinoma and total thyroidectomy with cervicocentral lymph node dissection was performed. However, the final histological examination revealed papillary hyperplasia and not a malignancy. Thyroid papillary hyperplasia presenting as a single thyroid nodule is rare. Nevertheless, the possibility of thyroid papillary hyperplasia should be considered when the features of fine needle aspiration cytology are suggestive, but not fully evident for papillary carcinoma. In these cases it is important to wait for the final histology and abandon frozen section examination.
在一名40岁左侧甲状腺叶有肿物的女性患者中,细针穿刺细胞学检查结果怀疑为甲状腺乳头状癌。随后进行了甲状腺半叶切除术及冰冻切片检查。冰冻切片也提示为乳头状癌,遂行甲状腺全切术及颈部中央淋巴结清扫术。然而,最终的组织学检查显示为乳头状增生而非恶性肿瘤。表现为单个甲状腺结节的甲状腺乳头状增生很罕见。尽管如此,当细针穿刺细胞学检查结果提示为乳头状癌但证据并不充分时,应考虑甲状腺乳头状增生的可能性。在这些病例中,等待最终的组织学检查结果并放弃冰冻切片检查很重要。