Kanjanavirojkul N, Puapairoj A, Patarapadungkit N
Department of Pathology, Faculty of Medicine, Khon Kaen University, Thailand.
J Med Assoc Thai. 2000 Apr;83(4):348-51.
A 9-year-old girl with a history of a palpable multinodular hard mass in the right lobe of the thyroid gland was biopsied. On diagnosis of a papillary carcinoma, total thyroidectomy and right radical neck dissection were performed. Examination of frozen sections demonstrated metastasis in the right but not the left cervical lymph nodes. Imprint cytology revealed small papillary sheets of neoplastic cells with a high proportion of cytoplasmic inclusions and a few nuclear grooves. These nuclear details allowed a specific diagnosis of metastatic papillary thyroid carcinoma. Papillary thyroid carcinoma can be easily diagnosed by imprint cytology. In places such as small and country hospitals that do not have pathology laboratories, it can also be used successfully as an alternative to frozen section histology. The efficiency, simplicity and rapidity of this method make it a very useful procedure.
一名9岁女孩，甲状腺右叶有可触及的多结节硬块病史，接受了活检。诊断为乳头状癌后，进行了全甲状腺切除术和右侧根治性颈淋巴结清扫术。冰冻切片检查显示右侧颈部淋巴结有转移，左侧没有。印片细胞学检查发现肿瘤细胞呈小乳头状片，细胞质内含物比例高，有一些核沟。这些核细节有助于对转移性甲状腺乳头状癌做出明确诊断。甲状腺乳头状癌通过印片细胞学检查很容易诊断。在没有病理实验室的小型乡村医院等地，它也可以成功地作为冰冻切片组织学检查的替代方法。这种方法的高效性、简便性和快速性使其成为一种非常有用的程序。
