Lertakyamanee Jariya, Ruksamanee Em-Orn, Tantiwong Anupan, Boonsuk Karuna, Nilpradab Ingporn, Vorakijpokatorn Puttipannee, Soontrapa Suchai
Department of Anesthesiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
J Med Assoc Thai. 2002 Dec;85(12):1288-95.
To advise a patient to have transurethral resection of prostate (TURP) needs information on the benefit and complications of the procedure. Quality assurance also needs present results to be compared with future ones.
The authors wanted to know: 1. Whether TURP can decrease theInternational prostate symptom score (IPSS) and improve the Quality of Life (QOL) scores concerning urination at 1.5 months post-operatively for at least 25 per cent of the pre-operative scores?; 2. What are the common medical diseases in this type of patient?; and 3. What are the mortality and immediate complications of TURPF?
This was a prospective, before-after design trial. All patients who came to have TURP at a tertiary care hospital were studied. IPSS and QOL scores were recorded before surgery and again when the patients came back to follow up at 1.5 months after discharge. Patients were evaluated for cardiopulmonary reserve and congestive heart failure. Anesthetic technique of choice was spinal anesthesia with 0.5 per cent bupivacaine. Anesthetic and surgical complications were recorded if the definitions were met.
Pre-operative and 1.5 months post-operative scores were compared using paired t-test and 95 per cent confidence interval.
During the 13 months there were 269 consecutive males who received TURP. The mean +/- SD age was 70.4 +/- 8.8 years (range 35-97). The mean difference between pre- and post-operative IPSS was 6.7 +/- 9.1 (95% CI 5.2-7.8). Quality of Life also improved, the mean difference between pre- and post-operative QOL was 3.2 +/- 1.6 (95% CI 2.9-3.5). Most patients had ASA class 2. Common pre-operative existing diseases were hypertension (31.6%), ischemic heart disease (18.2%), diabetes (15.6%), and COPD (7.1%). Anesthetic techniques were spinal block (77.3%), epidural block (5.9%), continuous epidural (11.2%), and general anesthesia (5.6%). Intra-operative complications were reported and T URsyndrome occurred in 1 patient (0.37%). There was one surgical death 3 days post-operation, due to septic shock probably from bowel perforation.
The patients' symptoms and quality of life significantly improved, but there was 1 surgical death and 1 TUR syndrome among 269.
建议患者进行经尿道前列腺切除术(TURP)需要了解该手术的益处和并发症相关信息。质量保证也需要将当前结果与未来结果进行比较。
作者想了解:1. TURP术后1.5个月时,国际前列腺症状评分(IPSS)是否能降低,排尿相关生活质量(QOL)评分是否能提高,且至少达到术前评分的25%?2. 这类患者常见的内科疾病有哪些?3. TURP的死亡率和近期并发症是什么?
这是一项前瞻性前后对照设计试验。对所有到三级护理医院接受TURP的患者进行研究。术前记录IPSS和QOL评分,患者出院后1.5个月复诊时再次记录。评估患者的心肺储备和充血性心力衰竭情况。首选的麻醉技术是0.5%布比卡因腰麻。若符合定义,则记录麻醉和手术并发症。
采用配对t检验和95%置信区间比较术前和术后1.5个月的评分。
在13个月期间,连续有269名男性接受了TURP。平均年龄±标准差为70.4±8.8岁(范围35 - 97岁)。术前和术后IPSS的平均差值为6.7±9.1(95%CI 5.2 - 7.8)。生活质量也有所改善,术前和术后QOL的平均差值为3.2±1.6(95%CI 2.9 - 3.5)。大多数患者ASA分级为2级。术前常见的现有疾病为高血压(31.6%)、缺血性心脏病(18.2%)、糖尿病(15.6%)和慢性阻塞性肺疾病(7.1%)。麻醉技术包括腰麻(77.3%)、硬膜外阻滞(5.9%)、连续硬膜外麻醉(11.2%)和全身麻醉(5.6%)。报告了术中并发症,1例患者发生TUR综合征(0.37%)。术后3天有1例手术死亡,可能因肠穿孔导致感染性休克。
患者的症状和生活质量显著改善,但269例患者中有1例手术死亡和1例TUR综合征。