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眼部白塞病的玻璃体切除术

Pars plana vitrectomy in ocular Behçet's disease.

作者信息

Soylu M, Demircan N, Pelit A

机构信息

Cukurova University School of Medicine, Department of Ophthalmology, Balcali, Adana, Turkey.

出版信息

Int Ophthalmol. 2001;24(4):219-23. doi: 10.1023/a:1022587012611.

DOI:10.1023/a:1022587012611
PMID:12678399
Abstract

PURPOSE

To evaluate the results of pars plana vitrectomy in Behçet patients with dense vitreous opacities, and its effect on intraocular inflammatory episodes and visual prognosis.

METHODS

The study group consisted of nine patients (one eye in eight patients, both eyes in one) with Behçet's disease who underwent pars plana vitrectomy because of dense vitreous opacification. The indications for vitrectomy, the effect of vitrectomy on the frequency of severe intraocular inflammatory episodes, and visual prognosis were investigated in these patients. All the patients were male, and their ages ranged between 28-45 years. Combined lensectomy was performed on those with complicated cataracts. The postoperative follow-up was between 12-66 months.

RESULTS

In all of the patients preoperative visual acuity was hand motions. Postoperatively there was no change in vision in five eyes, however visual acuity improved in five eyes, between counting fingers and 0.4. None of the patients showed any severe postoperative intraocular inflammatory episodes, and phthisis did not develop in any of the patients.

CONCLUSION

In this study, pars plana vitrectomy was found to have a beneficial effect on the prognosis of vision. There was also a decrease in the frequency of severe intraocular inflammatory episodes in patients with Behçet's disease with severe vitreous opacities, who did not respond to maximum medical treatment. However, further studies on larger groups should be performed in order to confirm the findings of this study.

摘要

目的

评估玻璃体切割术治疗伴有致密玻璃体混浊的白塞病患者的效果,及其对眼内炎症发作和视觉预后的影响。

方法

研究组由9例白塞病患者组成(8例单眼,1例双眼),这些患者因致密玻璃体混浊而接受了玻璃体切割术。对这些患者的玻璃体切割术指征、玻璃体切割术对严重眼内炎症发作频率的影响以及视觉预后进行了研究。所有患者均为男性,年龄在28至45岁之间。对合并白内障的患者进行了晶状体切除术。术后随访时间为12至66个月。

结果

所有患者术前视力均为手动。术后5只眼视力无变化,然而5只眼视力有所提高,介于指数和0.4之间。所有患者术后均未出现任何严重的眼内炎症发作,且无一例患者发生眼球痨。

结论

在本研究中,发现玻璃体切割术对视力预后有有益影响。对于接受最大程度药物治疗无效的伴有严重玻璃体混浊的白塞病患者,严重眼内炎症发作的频率也有所降低。然而,为了证实本研究的结果,应进行更大样本量的进一步研究。

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