Huang Russel C, Girardi Federico P, Poynton Ashley R, Cammisa Frank P
Hospital for Special Surgery, New York, NY, USA.
J Spinal Disord Tech. 2003 Apr;16(2):123-9. doi: 10.1097/00024720-200304000-00002.
This is a retrospective review of 32 patients with multilevel cervical myelopathy treated by laminectomy and lateral mass plate fusion. The prognosis of surgically treated myelopathy is evaluated as well as prognostic factors for recovery of myelopathy. Diagnoses included cervical spondylosis or ossification of the posterior longitudinal ligament. Final follow-up was at 15.2 months (mean) postoperatively. Myelopathy was graded preoperatively and postoperatively by the system of Nurick. All patients had preoperative radiographs and magnetic resonance imaging (MRI). The presence of abnormal T2-weighted MRI signal (myelomalacia) was noted. Postoperative studies included flexion-extension radiographs to assess fusion and MRI to evaluate decompression of neural elements and resolution of myelomalacia. Severity of preoperative Nurick myelopathy, presence of myelomalacia, and age were evaluated as potential prognostic indicators for surgically treated myelopathy. Mean Nurick score improved from 2.6 (range 1-4) to 1.8 (range 0-3) postoperatively (p < 0.0001). Twenty-two patients (71%) had improvement in Nurick grade of at least one point, and nine showed no improvement. No patients had deterioration of Nurick grade. Preoperative myelomalacia was noted in 15 (47%) patients, and all 15 had residual myelomalacia postoperatively. Severe myelopathy, age, and myelomalacia had no prognostic value for improvement of myelopathy. Complications included pseudarthrosis (3%), wound infection (9%), and transient C5 palsy (6%). This study demonstrates excellent outcomes from laminectomy and fusion in multilevel cervical myelopathy. A high rate of improvement of myelopathy was observed, neurologic deterioration did not occur, and complication rates were low. Severe myelopathy and myelomalacia on preoperative MRI had no prognostic value.
这是一项对32例接受椎板切除术和侧块钢板融合术治疗的多节段颈椎病患者的回顾性研究。评估了手术治疗颈椎病的预后以及颈椎病恢复的预后因素。诊断包括颈椎病或后纵韧带骨化。末次随访时间为术后平均15.2个月。术前和术后采用Nurick系统对颈椎病进行分级。所有患者术前行X线片和磁共振成像(MRI)检查。记录T2加权MRI信号异常(脊髓软化)的情况。术后检查包括屈伸位X线片以评估融合情况,MRI用于评估神经减压和脊髓软化的消退情况。术前Nurick颈椎病的严重程度、脊髓软化的存在情况和年龄被评估为手术治疗颈椎病的潜在预后指标。术后Nurick平均评分从2.6(范围1 - 4)改善至1.8(范围0 - 3)(p < 0.0001)。22例患者(71%)Nurick分级至少改善1分,9例无改善。无患者Nurick分级恶化。15例(47%)患者术前存在脊髓软化,术后这15例均有残留脊髓软化。严重颈椎病、年龄和脊髓软化对颈椎病的改善无预后价值。并发症包括假关节形成(3%)、伤口感染(9%)和短暂性C5麻痹(6%)。本研究表明,多节段颈椎病行椎板切除术和融合术的效果良好。观察到颈椎病改善率高,未发生神经功能恶化,并发症发生率低。术前MRI显示的严重颈椎病和脊髓软化无预后价值。