van Laarhoven Hanneke W M, Verstappen Carla C P, Beex Louk V A M, Kappelle Arnoud C, Punt Cornelis J A
Department of Medical Oncology, University Medical Centre St. Radboud, P.O. Box 9101, 6500HB Nijmegen, The Netherlands.
Anticancer Res. 2003 Jan-Feb;23(1B):647-8.
Peripheral neuropathy is a rare complication of the commonly used cytotoxic drug 5-fluorouracil (5-FU). We report a case of 5-FU-induced peripheral neuropathy in a patient with metastatic colorectal carcinoma. Discontinuation of 5-FU therapy is recommended in case of 5-FU-related neurotoxicity.
周围神经病变是常用细胞毒性药物5-氟尿嘧啶（5-FU）的一种罕见并发症。我们报告了1例转移性结直肠癌患者发生5-FU诱导的周围神经病变的病例。若出现与5-FU相关的神经毒性，建议停用5-FU治疗。
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