细针穿刺活检在骨病变的初始诊断中应用
Fine-needle aspiration biopsy in the initial diagnosis of bone lesions.
作者信息
Yamamoto Tetsuji, Nagira Keiko, Marui Takashi, Akisue Toshihiro, Hitora Toshiaki, Nakatani Tetsuya, Yoshiya Shinichi, Kurosaka Masahiro, Ohbayashi Chiho
机构信息
Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.
出版信息
Anticancer Res. 2003 Jan-Feb;23(1B):793-7.
BACKGROUND
The diagnostic role of fine-needle aspiration biopsy (FNAB) of bone lesions is not yet fully understood. The aim of this study was to examine the diagnostic accuracy and reliability of FNAB of bone lesions.
MATERIALS AND METHODS
FNAB smears of 73 lesions obtained from 70 patients with bone lesions were retrospectively reviewed randomly, combined with clinical and radiological findings.
RESULTS
Of the 73 FNAB cases analyzed, 67 (92%) were considered to be adequate for diagnosis. The sensitivity and specificity were 100% and 86%, respectively. The positive and negative predictive values were 94% and 100%, respectively. The specific FNAB diagnoses were correct in 63% of the benign group, 89% of the malignant group and 17% of the nonneoplastic group.
CONCLUSION
FNAB of bone is a simple, safe, rapid, reliable and cost-effective diagnostic procedure. FNAB is suggested to be helpful in the workup and management of patients with bone lesions.
背景
骨病变细针穿刺活检（FNAB）的诊断作用尚未完全明确。本研究旨在探讨骨病变FNAB的诊断准确性和可靠性。
材料与方法
回顾性随机分析70例骨病变患者的73处病变的FNAB涂片，并结合临床和影像学检查结果。
结果
在分析的73例FNAB病例中，67例（92%）被认为诊断充分。敏感性和特异性分别为100%和86%。阳性和阴性预测值分别为94%和100%。在良性组中，63%的特异性FNAB诊断正确；在恶性组中，89%诊断正确；在非肿瘤组中，17%诊断正确。
结论
骨FNAB是一种简单、安全、快速、可靠且经济有效的诊断方法。建议FNAB有助于骨病变患者的检查和管理。
Zotero 插件