用于心肌梗死检测/成像的微波断层扫描。I. 离体犬心。

Microwave tomography for detection/imaging of myocardial infarction. I. Excised canine hearts.

作者信息

Semenov Serguei Y, Bulyshev Alexander E, Posukh Vitaly G, Sizov Yuri E, Willams Thomas C, Souvorov Alexander E

机构信息

Biophysical Laboratory, Carolinas Medical Center, 1000 Blythe Blvd, Charlotte, NC 28203, USA.

出版信息

Ann Biomed Eng. 2003 Mar;31(3):262-70. doi: 10.1114/1.1553452.

DOI:10.1114/1.1553452

PMID:12680724

Abstract

We have demonstrated previously that the dielectric properties of myocardium at microwave spectrum are a sensitive indicator of its blood content, ischemia, and infarction. The purpose of this study is to validate the feasibility of microwave tomography for detection of myocardial infarction based on the differences in dielectric properties between normal and infarcted tissues. Excised canine heats with two weeks myocardial infarction were imaged. Tomographic imaging experiments were conducted using a three-dimensional (3D) microwave tomographic system operating at a frequency of 1.0 GHz. To obtain the images, we used 3D reconstruction algorithms. Images of excised canine hearts with myocardial infarction were obtained at a frequency of 1 GHz, applicable for whole body imaging. Microwave tomographic images were compared with anatomical slices. The comparison confirms that microwave tomography is capable of detection of myocardial infarction.

摘要

我们之前已经证明，心肌在微波频段的介电特性是其血液含量、缺血和梗死的敏感指标。本研究的目的是基于正常组织和梗死组织之间介电特性的差异，验证微波断层扫描检测心肌梗死的可行性。对患有两周心肌梗死的离体犬心脏进行成像。使用工作频率为1.0 GHz的三维（3D）微波断层扫描系统进行断层成像实验。为了获得图像，我们使用了3D重建算法。在1 GHz频率下获得了患有心肌梗死的离体犬心脏的图像，该频率适用于全身成像。将微波断层图像与解剖切片进行比较。比较结果证实微波断层扫描能够检测心肌梗死。