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微波断层扫描:用于生物成像的二维系统。

Microwave tomography: two-dimensional system for biological imaging.

作者信息

Semenov S Y, Svenson R H, Boulyshev A E, Souvorov A E, Borisov V Y, Sizov Y, Starostin A N, Dezern K R, Tatsis G P, Baranov V Y

机构信息

Laser and Applied Technologies Laboratory, Carolinas Heart Institute, Charlotte, NC, USA.

出版信息

IEEE Trans Biomed Eng. 1996 Sep;43(9):869-77. doi: 10.1109/10.532121.

Abstract

Microwave tomographic imaging is one of the new technologies which has the potential for important applications in medicine. Microwave tomographically reconstructed images may potentially provide information about the physiological state of tissue as well as the anatomical structure of an organ. A two-dimensional (2-D) prototype of a quasi real-time microwave tomographic system was constructed. It was utilized to reconstruct images of physiologically active biological tissues such as an explanted canine perfused heart. The tomographic system consisted of 64 special antennae, divided into 32 emitters and 32 receivers which were electronically scanned. The cylindrical microwave chamber had an internal diameter of 360 mm and was filled with various solutions, including deionized water. The system operated on a frequency of 2.45 GHz. The polarization of the incident electromagnetic field was linear in the vertical direction. Total acquisition time was less than 500 ms. Both accurate and approximation methods of image reconstruction were used. Images of 2-D phantoms, canine hearts, and beating canine hearts have been achieved. In the worst-case situation when the 2-D diffraction model was used for an attempt to "slice" three-dimensional (3-D) object reconstruction, we still achieved spatial resolution of 1 to 2 cm and contrast resolution of 5%.

摘要

微波断层成像技术是一项具有在医学领域重要应用潜力的新技术。微波断层重建图像有可能提供有关组织生理状态以及器官解剖结构的信息。构建了一个二维(2-D)准实时微波断层成像系统原型。它被用于重建诸如离体犬类灌注心脏等生理活性生物组织的图像。该断层成像系统由64个特殊天线组成,分为32个发射器和32个接收器,这些天线进行电子扫描。圆柱形微波腔室内径为360毫米,内部充满各种溶液,包括去离子水。该系统工作频率为2.45吉赫兹。入射电磁场的极化在垂直方向上是线性的。总采集时间不到500毫秒。使用了图像重建的精确方法和近似方法。已获得二维体模、犬类心脏以及跳动的犬类心脏的图像。在最坏的情况下,当使用二维衍射模型试图“切片”三维(3-D)物体重建时,我们仍实现了1至2厘米的空间分辨率和5%的对比度分辨率。

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