Sparkes C G
Br J Dermatol. 1976 Mar;94 suppl 12:77-82. doi: 10.1111/j.1365-2133.1976.tb02273.x.
A number of studies describing the effects on pituitary adrenal function of topically applied corticosteroids are reviewed. It is concluded that the adrenal function of the majority of out-patients is little affected by treatment with correctly prescribed topical corticosteroids. However, where patients need brief periods of treatment with large quantities of potent topical corticosteroids for extensive disease, clinicians should be aware of the possibility of transient adrenal suppression.
本文综述了多项描述局部应用皮质类固醇对垂体肾上腺功能影响的研究。得出的结论是,大多数门诊患者的肾上腺功能受正确处方的局部皮质类固醇治疗的影响很小。然而,对于患有广泛性疾病且需要短期大量使用强效局部皮质类固醇进行治疗的患者,临床医生应意识到短暂肾上腺抑制的可能性。