Schaller B
Klinik für Schädel-, Kiefer- und Gesichtschirurgie, Universitätsspital, Bern.
HNO. 2003 Apr;51(4):284-95. doi: 10.1007/s00106-002-0797-3.
Cerebellopontine angle tumors, although uniform in location, are diverse with regard to the site of tumor origin and displacement of the neurovascular structures. With the increasing use of magnetic resonance imaging in the diagnosis of brain lesions, the treatment of tumors of the cerebellopontine angle has changed extraordinarily. An appreciation of the vascular and cranial nerve microanatomy and the intimate relationship between neurovascular structures and the tumor is essential for achieving optimal surgical results
A review was made of the current literature.
The different treatment options are compared with microsurgical tumor resection with respect to neurological outcome and long-term follow-up. As microsurgical removal is still the treatment of choice for such tumors, the indication for surgical treatment is analyzed and the different surgical approaches to the cerebellopontine angle are described in terms of their frequency of involvement in the surrounding neural and vascular structures with varying tumor size. The etiology of facial and cochlear nerve injury, as well as complications involving other cranial nerves, are discussed with emphasis on pathophysiological and anatomical considerations. In conclusion, the great variation in the anatomical location and the involvement of neurovascular structures in the cerebellopontine angle is demonstrated.
桥小脑角肿瘤虽然位置统一,但肿瘤起源部位和神经血管结构移位情况各不相同。随着磁共振成像在脑病变诊断中的应用日益增加,桥小脑角肿瘤的治疗发生了巨大变化。了解血管和颅神经显微解剖结构以及神经血管结构与肿瘤之间的密切关系对于获得最佳手术效果至关重要。
对当前文献进行了综述。
将不同的治疗方案与显微手术肿瘤切除术在神经学结果和长期随访方面进行了比较。由于显微手术切除仍是此类肿瘤的首选治疗方法,因此分析了手术治疗的适应证,并根据不同肿瘤大小对周围神经和血管结构的累及频率描述了桥小脑角的不同手术入路。讨论了面神经和耳蜗神经损伤的病因以及涉及其他颅神经的并发症,重点是病理生理和解剖学方面的考虑因素。总之,展示了桥小脑角解剖位置的巨大差异以及神经血管结构的累及情况变化。