白色念珠菌性心内膜炎的治疗：病例报告及文献综述

Treatment of Candida albicans endocarditis: case report and a review.

作者信息

Hauser M, Hess J, Belohradsky B H

机构信息

Dept. of Pediatric Cardiology, German Heart Center, Lazarettstrasse 36, D-80636 Munich, Germany.

出版信息

Infection. 2003 Mar;31(2):125-7. doi: 10.1007/s15010-002-2187-x.

DOI:10.1007/s15010-002-2187-x

PMID:12682821

Abstract

Candida albicans endocarditis occurs mostly in patients with congenital heart disease; open heart surgery is the greatest predisposing factor. We report on a child with truncus arteriosus communis and a large Candida vegetation within the prosthetic pulmonary valve, causing severe right ventricular outflow tract obstruction. Treatment was performed successfully by surgery and administration of liposomal amphotericin B (AmBisome) and 5-flucytosine.

摘要

白色念珠菌性心内膜炎多见于先天性心脏病患者；心脏直视手术是最大的诱发因素。我们报告一例患有共同动脉干的儿童，其人工肺动脉瓣内有一大块念珠菌赘生物，导致严重的右心室流出道梗阻。通过手术以及给予脂质体两性霉素B（安必素）和5-氟胞嘧啶成功进行了治疗。